Attack – Saka, Aubameyang, Smith Rowe
Odegaard comes into the side in place of Alexandre Lacazette.
Lacazette has started the last four matches but has not scored in that time.
Pierre-Emerick Aubameyang was not at his best against Liverpool but will keep his spot after scoring in four of the last five home matches.
Emile Smith Rowe has been the standout player so far this season for the Gunners.
He and Bukayo Saka will once again keep club-record signing Nicolas Pepe out of the team.
Arsenal’s expected line-up vs Newcastle in full: Ramsdale; Tomiyasu, White, Gabriel, Tierney; Partey, Sambi Lokonga; Saka, Odegaard, Smith Rowe; Aubameyang.